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Buy BPC-157 Peptide

BPC-157, known as the “Body Protection Compound”, is a stable gastric pentadecapeptide derived from a partial sequence of body protection compound beneficial in healing numerous types of damaged tissues, including tendons, ligaments, the digestive tract, and even the central nervous system.

Shop our Full Range of BPC-157 Peptides

What Is The BPC-157 Mechanism Of Action?

BPC-157, is a fragment of the Body Protection Compound (BPC), it was originally identified and extracted from human gastric juice. The peptide is thought to work by modulating key biological processes important for healing and protection.

It boosts the body’s natural repair mechanisms, notably by promoting angiogenesis, or the formation of new blood vessels. This is vital for getting nutrients and oxygen to injured tissues to speed up wound healing. The peptide also affects the expression of growth factors like VEGF (vascular endothelial growth factor), enhancing angiogenesis and tissue repair.

Furthermore, BPC-157 has been shown to modulate the protective mechanisms in the gastrointestinal tract, reducing inflammation and mitigating the effects of damage caused by toxins or medications. It does this, in part, by stabilising the integrity of the gut lining and promoting the regeneration of the damaged cells, which is essential for the healing of stomach ulcers and combating conditions like inflammatory bowel disease and leaky gut syndrome.

On a cellular level, Body Protection Compound 157 enhances the upregulation of genes involved in the cytoskeleton, which encompasses the structure and transport within cells, thereby facilitating the healing and rebuilding of injured tissues. By impacting several pathways involved in the healing process, including anti-inflammatory responses and the modulation of genes responsible for regeneration and repair, the peptide exhibits a broad scope of action that contributes to its potential therapeutic use in a wide range of conditions.

BPC-157 Structure
Source: PubChem

Structure of BPC-157

Sequence: H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH.

Molecular Formula: C62H98N16O22

Molecular Weight: 1419.5 g/mol

What Are The Research Benefits of BPC-157?

Promotion of tissue healing: Extensive research on BPC-157 suggests it enhances the production of reticulin and collagen, in addition to promoting angiogenesis. It further encourages the infiltration of macrophages and fibroblasts, highlighting its potential as an effective therapeutic agent in wound management. Studies have demonstrated its ability to expedite the healing process of musculoskeletal soft tissues, underlining its therapeutic significance [1].

Anti-inflammatory properties: Japan Studies suggest the peptide exhibits anti-inflammatory effects, potentially modulating the body’s inflammatory response to injury or disease [2].

The peptide has shown efficacy in treating skin burns, gastro intestinal cramps, Crohn’s disease, and inflammatory bowel conditions such as stomach ulcers by reducing inflammation and promoting the health of the GI tract and blood vessels. 

Neuroprotective effects: One study suggested the peptide may counteract damage caused by paracetamol-induced convulsions and brain damage in rats [2].

Potential treatment for knee pain: Initial studies suggest intra-articular injection of Body Protection Compound 157 may help alleviate multiple types of knee pain [3].

Esophagocutaneous fistula healing therapy: Application of the peptide may precipitate therapeutic benefits in esophagocutaneous fistula healing according to research [4].

Antioxidant activities: According to Japan research, engineered Lactococcus lactis as a delivery vehicle for BPC-157 demonstrates antioxidant activity, reducing ROS production in cell models [5].

Cytoprotective properties: Research has demonstrated that BPC 157 may serve as a useful cytoprotective peptide therapy in heart disturbances, myocardial infarction, and heart failure [6].

Potential treatment for abdominal aorta anastomosis: The peptide shows immediate benefits when applied as a bath immediately after anastomosis [7].

Cardiovascular health: Recent studies suggest the peptide may influence nitric oxide pathways, enhancing its therapeutic potential. By promoting nitric oxide production, the peptide can improve endothelial function, reduce oxidative stress, and support angiogenesis. This interaction benefits cardiovascular health and supports the peptide’s overall healing abilities. 

Improved healing of esophagogastric anastomosis: Studies have shown the application of BPC-157 and L-arginine improved the healing process in rats [8].

Drug Side-Effect Mitigation: The peptide has demonstrated significant potential in reducing side effects of various medications, especially NSAIDs, known for their gastrointestinal risks.

By healing the gut lining and decreasing inflammation, the peptide provides a protective layer against drug-induced damage, thus improving the body’s resilience to the negative effects of some pharmaceuticals.

This makes the body protection compound 157 an interesting candidate in pharmacology as a supportive agent in drug therapy to prevent common drug-related issues [9].

Colony Collapse Disorder (CCD): In addition to its therapeutic potentials in humans, there’s emerging interest in exploring the effects of BPC-157 on animal health, such as its potential role in addressing Colony Collapse Disorder (CCD) in honey bees, a phenomenon that threatens global bee populations and, by extension, global agriculture [10].

Future research: It’s crucial to acknowledge that the majority of these studies have been performed in vitro or on animal subjects. 

Although the potential benefits of human consumption appear promising, especially for conditions such as leaky gut and assisting in the recovery from tendon and ligament injuries, caution must be exercised when introducing products like BPC-157 5mg into the body. Self-administration without professional guidance is strictly forbidden.

Despite its promising therapeutic benefits, further research is needed to fully understand the implications and safety profile of BPC-157’s use in human medicine.

Buy BPC-157 Capsules for research online today!

Buy BPC-157 and VIP (Vasoactive Intestinal Peptide) Peptide Stack

BPC-157 VIP Peptide Stack

Explore the BPC-157 and VIP Peptide Stack, a potent combination designed to harness the healing properties of two respected peptides in modern medicine. This formula combines Body Protection Compound 157, known for its tissue repair, blood vessel growth, and anti-inflammatory benefits, with VIP (Vasoactive Intestinal Peptide), renowned for its neuroprotection, anti-inflammatory, and cell protection advantages. Together, they offer a powerful duo for healing and recovery, aiding research into issues like gastrointestinal disorders or musculoskeletal injuries. Buy BPC-157 2 mg and VIP 2mg Peptide Stack today!

Don’t forget to buy bacteriostatic water for reconstitution.

Buy BPC-157 and TB-500 Blend Peptide Nasal Spray

tb500-bpc157-blend-nasal-spray-30ml

Explore our cutting-edge BPC-157 and TB-500 Blend Nasal Spray, crafted specifically for research purposes. This innovative formula combines the tissue healing and protective benefits of BPC-157 with the remarkable ability of TB-500 to enhance muscle repair and reduce inflammation.

Its efficient nasal delivery system offers a novel method for investigating the effects of peptides on recovery and tissue regeneration. Ideal for Japan researchers dedicated to pioneering advancements in tissue repair, injury recuperation, and inflammation control. Discover how our nasal spray can elevate your research in tissue regeneration. Buy BPC-157 and TB-500 Blend Nasal Spray.

BPC-157 FAQ’s

What is BPC-157 and how does it work?

Body Protection Compound 157 is a synthetic peptide derived from a protein found in stomach acid. Originally developed to combat stomach ulcers, it is believed to promote healing by enhancing angiogenesis, the process of blood vessel formation, which improves the delivery of nutrients and oxygen to damaged tissues. It also modulates several biological processes that are crucial for healing, including reducing inflammation and protecting cells from damage.

Is BPC-157 safe for human use?

While BPC-157 has demonstrated significant potential in various animal studies and laboratory experiments regarding healing and recovery, it remains classified as a research chemical. Its safety and efficacy for human use have not been confirmed through comprehensive human clinical trials.

In the United States, the Food and Drug Administration (FDA) has not approved medical institutions to buy BPC-157 for medical use, indicating that it does not meet the agency’s stringent safety and efficacy standards. Similarly, in the United Kingdom, the Medicines and Healthcare products Regulatory Agency (MHRA) has yet to authorise BPC-157 for therapeutic use.

As a result, you can only buy BPC-157 strictly for scientific and educational research purposes and not for human consumption.

Can BPC-157 be used to treat specific conditions?

Japan Research on this peptide suggests it may have potential in treating a variety of conditions such as gastrointestinal disorders, muscle and tendon injuries, and inflammatory conditions due to its regenerative and protective properties. However, further vitro testing is needed to fully understand its therapeutic applications and efficacy.

How is BPC-157 administered?

BPC-157 can be administered in various forms, including injections and oral supplements. Additionally, innovative delivery systems such as nasal sprays are being explored to increase its efficacy and accessibility for research purposes.

Where can BPC-157 be purchased?

You can buy BPC-157 from specialized peptide and research chemical suppliers, such as Direct Peptides Japan. It is important to note that its conditions of use is marketed and sold for Japan research purposes only and not for human consumption.

What are the possible side effects of BPC-157?

Due to the limited research on human subjects, the range of possible side effects of BPC-157 is not fully understood. Animal studies have not shown significant adverse effects at therapeutic dosages. However, as with any experimental treatment, potential risks and side effects may exist.
For more detailed information and updates on the peptides research, always refer to the latest scientific literature and clinical trial data.

Which is better BPC-157 Oral vs. Injection?

The administration of BPC-157, whether through oral ingestion (as a tablet) or via injection, is primarily determined by the research context and the particular tissues or conditions being investigated. Opting for oral intake is often favored for gastrointestinal concerns when aiming to buy BPC-157, as it enables the peptide to directly engage with the gut lining, promoting regenerative benefits.

When looking to buy BPC-157, injections (whether subcutaneous or intramuscular) offer a more focused strategy, particularly beneficial for conditions such as musculoskeletal injuries, granting direct entry to the impacted tissues. Each approach, whether oral ingestion or injection, presents distinct advantages, and the decision on whether to opt for oral or injectable forms should be guided by the precise objectives and framework of the research.

Buy Peptide Capsules online for research from Direct Peptides Japan.

Does BPC-157 work for muscle growth?

Preliminary research and Japan animal studies indicate that Body Protection Compound 157 may benefit muscle growth by enhancing muscle and tendon healing and increasing blood flow to injuries. This could lead to quicker recovery from muscle damage and indirectly boost muscle growth and endurance through better healing processes. However, BPC-157’s direct impact on human muscle growth hasn’t been definitively proven, necessitating further research to fully grasp its effects and how it works. It’s important to remember that the peptide is a research chemical, therefore product usage is intended for scientific and educational research only.

Can BPC-157 help treat arthritis?

Research into BPC-157 has indicated potential benefits in treating arthritis, primarily through its regenerative properties and its ability to enhance angiogenesis. This peptide is thought to promote the healing of joint tissues and reduce inflammation, factors critical in the management of arthritis symptoms.

While Japan studies in animal models have shown promising results, further research in humans is necessary to ascertain the efficacy and safety of BPC-157 in treating arthritis. It’s important to note that current interest in the peptide’s applications for arthritis remains within the realm of scientific research, and it is not yet approved for clinical use in treating this condition.

BPC-157 versus TB500, which is better?

Deciding whether to buy BPC-157 or TB500 and which is better depends on the specific research or therapy goals. Both peptides are known for their healing properties but work differently. Body Protection Compound 157 is famous for regenerating tendons, muscles, and the gastrointestinal tract, promoting blood vessel growth and reducing inflammation. TB500 (thymosin beta-4) is known for its role in increasing actin, crucial for cell movement and tissue repair.

BPC-157 may be better for musculoskeletal and inflammatory issues, while TB500 might be preferred for broader tissue repair due to its actin regulation. The choice should be based on the research objectives, condition under study, and desired outcomes. Note that both peptides are research chemicals, with their effectiveness and safety in humans not fully proven.

How does BPC-157 and TB500 work together?

Combining BPC-157 and TB500 could enhance their healing effects due to their complementary actions. BPC-157 boosts tissue regeneration, healing, and angiogenesis, helping muscles, tendons, and the gastrointestinal tract recover quickly. TB500 improves tissue repair and cell movement by regulating actin, essential for cell shape and movement.

Together, these peptides may provide a synergistic effect, leading to faster and more comprehensive healing, especially useful for complex or chronic conditions needing both tissue repair and anti-inflammatory effects. However, the enhanced benefits of combining BPC-157 and TB500 are still theoretical and require more research to fully understand their effects and ensure safe use.

Buy BPC-157 and TB500 peptide blend from Direct Peptides Japan

Summary of Research Applications

  • Promotes soft tissue healing such as tendons and muscles
  • Heals wounds faster
  • Joint pain relief
  • Neuroprotective effects
  • Cardiovascular health
  • Anti-inflammatory
  • Gastrointestinal health
  • Mitigates side effects of drugs
  • Influence on angiogenesis
  • CCD (Colony Collapse Disorder) in honey bees

BPC-157 Peptide Quality Assured

At Direct Peptides Japan, we redefine excellence in peptide solutions, providing BPC-157 peptides guaranteed to be 99% pure. Our rigorous synthesis process is designed to ensure that each batch exceeds industry standards for quality and efficacy, reflecting our unparalleled commitment to precision and excellence.

Our commitment to premium purity not only reinforces our standing for outstanding quality but also enhances the therapeutic efficacy of BPC-157. This ensures our clients receive a product that meets their research requirements with unmatched dependability.

View the HPLC Certificate here.

References For Further Reading​

[1] D.Gwyer, N.M.Wragg & S.L.Wilson (2019) Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing – Cell and Tissue Research Volume 377, pages 153–159, 27 March 2019.

[2] S.Llic et al. (2010) High hepatotoxic dose of paracetamol produces generalized convulsions and brain damage in rats. A counteraction with the stable gastric pentadecapeptide BPC 157 (PL 14736) – Journal of Physiology and Pharmacology 2010, 61, 2, 241-250

[3] E.Lee and Padgett (2021) Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain – Alternative Therapies in Health and Medicine, 2021 Jul;27(4):8-13.

[4] V.Cesarec et al (2013) Pentadecapeptide BPC 157 and the esophagocutaneous fistula healing therapy – European Journal of Pharmacology, Volume 701, Issues 1–3, 15 February 2013, Pages 203-212. 

[5] K.Skrlec et al (2018) Engineering recombinant Lactococcus lactis as a delivery vehicle for BPC-157 peptide with antioxidant activities – Applied Microbiology and Biotechnology, 06 September 2018, Volume 102, pages 10103–1011.

[6] P.Sikiric et al. (2022) Stable Gastric Pentadecapeptide BPC 157 as Useful Cytoprotective Peptide Therapy in the Heart Disturbances, Myocardial Infarction, Heart Failure, Pulmonary Hypertension, Arrhythmias, and Thrombosis Presentation – Biomedicines, 2022 Oct 25;10(11):2696.

[7] M.Hrelec et al (2009) Abdominal aorta anastomosis in rats and stable gastric pentadecapeptide BPC 157, prophylaxis and therapy – Journal of Physiology and Pharmacology, 2009 Dec:60 Suppl 7:161-5.

[8] Z.Djakovic et al (2016) Esophagogastric anastomosis in rats: Improved healing by BPC 157 and L-arginine, aggravated by L-NAME – World Journal of Gastroenterology, 2016 Nov 7; 22(41): 9127–9140.

[9] N.Jelovac et al (1999) Pentadecapeptide BPC 157 attenuates disturbances induced by neuroleptics: the effect on catalepsy and gastric ulcers in mice and rats – European Journal of Pharmacology, 1999 Aug 20;379(1):19-31.

[10] I.T.Gajger et al (2018) Stable gastric pentadecapeptide BPC 157 in honeybee (Apis mellifera) therapy, to control Nosema ceranae invasions in apiary conditions – Journal of Veterinary Pharmacology and Therapeutics, 2018 Aug;41(4):614-621.

Why Choose Direct Peptides Japan?

Buy BPC-157 today and discover unrivalled quality with Direct Peptides Japan, your premier source for BPC-157 peptides. Setting us apart is our unique array of body protection compound 157 formulations, including peptide vials available in 2mg, 5mg and 10mg, peptide blends and stacks with potential synergistic effects, peptide nasal sprays available in 15ml and 30ml spray bottles, pre-mixed peptide pens, and even peptide capsules. Catering to varied research needs, we ensure that Japan researchers have access to the precise formulation required for their specific projects.

ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.

DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Japan Direct Peptides website: https://japan.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.