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Highest Quality | For Research Use Only


Buy MGF Peptide Japan

Mechano Growth Factor (MGF) is an alternative form of IGF-1 (insulin-like growth factor -1), produced by a frame shift in the IGF gene. MGF plays crucial roles in muscle development and repair, making it a focal point in the field of regenerative medicine and athletic performance enhancement.

Upon mechanical overload or damage to muscle tissue, MGF is expressed locally within the damaged muscle fibers and acts to initiate satellite cell proliferation. Satellite cells are quiescent muscle stem cells that can be activated in response to muscle injury or exercise. The activation of these cells by MGF allows for the fusion to existing muscle fibers, promoting hypertrophy and enhancing the body’s ability to repair muscle damage.

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Potential Benefits of MGF Peptide (Mechano Growth Factor)

  • Enhanced Muscle Recovery and Building: MGF is reported in studies to be beneficial for individuals requiring enhanced recovery and muscle building, particularly after eccentric muscle loading [1].
  • Activation of Muscle Satellite Cells: Research indicates MGF has shown potential in activating muscle satellite cells, which play a critical role in muscle repair and regeneration [2].
  • Nutrient Movement into Muscle Cells: Some research indicates that MGF might facilitate nutrient movement into muscle cells, enhancing muscle growth and recovery [3].
  • Anti-apoptotic Properties: According to research, MGF has displayed anti-apoptotic properties, able to protect adult cardiomyocytes after infarction. The E-domain of MGF appears to have specific significance in this context [4].
  • Promotion of Osteoblast Proliferation and Bone-defect Healing: MGF-Ct24E, a variant of MGF, has been reported to have positive effects on osteoblast proliferation and bone-defect healing [5].
  • Neuroprotective Effects: Some studies have suggested MGF’s potential neuroprotective effects, although further research is needed to confirm these findings [6].
  • Promotes Muscle Repair and Growth: Scientific studies indicate MGF has shown promise in promoting muscle repair and growth, potentially offering benefits for those with muscle loss due to aging or specific conditions [7].
  • Improved Cardiac Function: Research has indicated that MGF can improve cardiac function, potentially offering therapeutic benefits for cardiovascular health [8].
  • Increased Bone Density: Some studies have suggested that MGF might contribute to increased bone density [9].
  • Speeds up Injury Repair Process: MGF has been reported to speed up the injury repair process, potentially offering benefits in the management of sports injuries [10].


[1] https://www.sciencedirect.com/science/ article/abs/pii/S0047637411000297

[2] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC1571137/

[3] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC10281885/

[4] https://www.sciencedirect.com/science/ article/abs/pii/S0142961214013003

[5] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC3167400/

[6] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC5501366/

[7] https://www.mdpi.com/1422-0067/23/8/4331

[8] https://link.springer.com/ article/10.1007/s11010-013-1689-4

[9] https://pubmed.ncbi.nlm.nih.gov/25129046/

[10] https://pubmed.ncbi.nlm.nih.gov/17984193/



DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Peptides website: https://japan.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.