£103.13 – £112.11
Buy PNC-27 Peptide Vial
PNC-27 is a peptide designed to treat cancer by targeting and destroying the cell membranes of cancer cells while leaving healthy cells unharmed. It works by binding to the HDM-2 protein found in cancer cells, which leads to the formation of membrane pores that cause cell death.
542 in stock
This product is intended for research purposes only. To be used by trained professionals only.
PNC-27 is a synthetic peptide that research suggests triggers necrosis in cancerous cells, resulting in cell death. In addition, an HDM-2 binding domain in the peptide allows it to membranolyze cancer cells and kill them [1].
Japan Scientific studies suggest PNC-27 peptide appears to be highly effective in treating a variety of cancers, including breast cancer, melanoma, pancreatic cancer, and leukaemia, according to experiments on animal subjects [2].
Some Japan studies have suggested in contrast to chemotherapy, which targets healthy cells, the PNC-27 peptide targets cancer cells. When it attaches to cancer cells, it makes holes in their membranes, causing them to die quickly.
Scientists had intended to use PNC-27 peptide to fight HIV until it was discovered that it could also be used to destroy cancer cells while not harming healthy ones. Few clinical trials using PNC-27 since then have shown that it is effective in combating cancer [3].
PNC 27’s mechanism of action, according to the studies, is caused by the formation of oligomeric pores in cancer cells’ plasma membranes. Researchers, therefore, concluded that these findings confirm cancer cells’ unique localization of MDM2 variants. Consequently, it was also stated that the future anticancer treatment using the PNC-27 peptide shows excellent promise.
References:
[1] http://www.annclinlabsci.org/ content/44/3/241.full
[2] https://touroscholar.touro.edu/ sjlcas/vol13/iss2/7/
[3] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC5359827/
Molecular Formula: C188H293N53O44S
Molecular Weight: 4031.7
Storage: Lyophilized peptides stored below -18°C.
Research use only. Not for human or animal consumption!
ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.
DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Japan Direct Peptides website: https://japan.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.
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