£105.71 – £285.40
Nontoxic protein that can selectively bind to receptors present in cancer cells to cause cell death.
Pre Mixed Cartridge and Kit:
*
1 x Cartridge (The cartridge is premixed with the peptide vial of your choice and Bacteriostatic Water)
* 1 x Peptide Cartridge Pen
* 1 x Pen Carry Case
* 3 x Pen Needle Tips
Single Mixed Cartridges (1,2 & 3) Come with:
* 1,2 or 3 x Cartridge (The cartridge is premixed with the peptide vial of your choice and Bacteriostatic Water)
* 3 x Pen Needle Tips
The single 1,2 & 3 cartridges do not come with a kit. Save 10% when buying 3 cartridges.
663 in stock
This product is intended for research purposes only. To be used by trained professionals only.
PNC-27 is a peptide that has sparked interest in the scientific community due to its anti-cancer capabilities. This membrane-active peptide contains an HDM-2-binding domain that correlates to p53 residues, a protein known for its function in cancer prevention, as well as a transmembrane-penetrating sequence [1].
As an intact peptide, PNC-27 pre mixed peptide has been shown in studies to promote cancer cell necrosis. PNC-27 has been shown in Japan studies to produce these effects in a number of breast cancer cells, including MCF-7, MDA-MB-468, and MDA-MB-157 [1]. PNC-27 interacts to HDM-2 in cancer cells when treated with this peptide, according to additional research. One study, for example, incubated double-fluorophore-labelled PNC-27 (50 g/ml) with 1106 MIA-PaCa-2 cells for 4 hours, indicating substantial interactions [2].
PNC-27 pre mixed peptide has also being investigated as a potential technique for early cancer detection. One study looked examined PNC-27 peptide attached PEI-superparamagnetic iron oxide nanoparticles (SPIONs) as a dual targeting agent for cancer detection in the early stages [3].
PNC-27’s efficacy against colon adenocarcinoma and ovarian cancer has also been studied in vitro and in vivo. various trials have yielded promising results, indicating that PNC-27 peptide has the potential to be an effective alternative treatment for various types of malignancies [4].
However, despite its promise, further research is required to properly understand the potential advantages and hazards of PNC-27 pre mixed peptide.
[1] https://link.springer.com/article/ 10.1007/s00280-009-1166-7
[2] https://www.pnas.org/doi/abs/ 10.1073/pnas.0909364107
[3] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC9588323/
[4] https://www.sciencedirect.com/ science/article/abs/pii/S17732247 22000892
Molecular Formula: C188H293N53O44S
Molecular Weight: 4031.7
Storage: Lyophilized peptides stored below -18°C.
Research use only. Not for human or animal consumption!
ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.
DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Japan Direct Peptides website: https://japan.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.
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